B-Complex is a synergistic combination of all the essential B vitamins. The best way to get all the essential B vitamins in therapeutic amounts is to consume a diet that is rich in whole grains, fruits, and vegetables. However, because most individuals do not meet this daily requirement, supplementation may be essential to minimize deficiency risk. Most commercially available B-Complex supplements feature vitamins either as (1) synthetic isolates, which include vitamins created wholly in a lab from industrial chemicals and solvents; (2) fermented nutrients, which are created by taking synthetic vitamin isolates and making them more bioavailable by fermenting them in nutritional yeast and/or probiotics; and/or (3) whole-food/food-sourced nutrients, which are vitamins concentrated from natural food sources (e.g. herbs, fruits, spices, & vegetables).