You've probably heard:
"Your labs are normal."
"Maybe it's just stress."
"Let's try another medication."
…but your body is still screaming for help.
There's a Name for This
Chronic Inflammatory Response Syndrome
CIRS is a whole-body inflammatory condition triggered by biotoxins like mold, Lyme, or post-infection illness (including COVID).
It shuts down your mitochondria's ability to produce energy, hijacks your immune system's intelligence, and creates neuroinflammation—often called "leaky brain"—alongside leaky gut issues.
CIRS can also trigger MCAS (mast cell activation syndrome) and histamine intolerance, leaving you chasing food eliminations—when the real culprit isn't the food at all.
And most doctors miss it.
CIRS Symptoms: The Full Picture
CIRS affects virtually every system in your body. If you're experiencing multiple symptoms from different categories below, it's time to get tested.
Neurological & Cognitive
- •Brain fog
- •Poor short-term memory
- •Difficulty concentrating
- •Word-finding problems
- •Confusion or disorientation
- •Dizziness or vertigo
- •Tingling or numbness in extremities
- •Headaches or migraines
- •Light sensitivity
- •Sound sensitivity
- •Mood swings, anxiety, or depression
- •Sleep disturbances (insomnia or unrestful sleep)
Immune & Inflammatory
- •Frequent or chronic infections
- •New allergies or worsening of existing allergies
- •Mast Cell Activation Syndrome (MCAS) symptoms
- •Histamine intolerance
- •Autoimmune flare-ups
Musculoskeletal
- •Muscle weakness
- •Muscle cramps or aches
- •Joint pain or stiffness
- •Exercise intolerance
- •Chronic fatigue or post-exertional malaise
Digestive
- •Bloating and gas
- •Diarrhea or constipation
- •Leaky gut symptoms
- •Food sensitivities that seem to "grow" over time
- •Malabsorption (not benefiting from supplements/foods)
- •Nausea
Hormonal / Endocrine
- •Adrenal dysfunction (wired but tired)
- •Thyroid imbalances
- •Irregular menstrual cycles or worsening PMS
- •Low libido
Respiratory
- •Shortness of breath
- •Sinus congestion or chronic sinus infections
- •Cough or throat irritation
- •Asthma-like symptoms
Other Common Symptoms
- •Temperature dysregulation (feeling unusually hot or cold)
- •Excessive thirst or frequent urination
- •Static shocks (due to electrolyte shifts)
- •Red or irritated eyes
- •Skin rashes or unexplained itching
- •Weight gain or sudden weight loss without explanation
Recognizing 3 or more of these symptoms across different categories? It's time to take the quiz.
Common Symptoms
Do These Sound Familiar?
Tap or hover over each card to see specific symptoms
Cognitive Function
- Brain fog
- Poor short-term memory
- Difficulty concentrating
- Word-finding problems
- Confusion or disorientation
Neurological & Sensory
- Dizziness or vertigo
- Tingling or numbness
- Headaches or migraines
- Light sensitivity
- Sound sensitivity
Mental Health & Sleep
- Mood swings
- Anxiety
- Depression
- Sleep disturbances
- Insomnia or unrestful sleep
Immune & Inflammatory
- Frequent infections
- New/worsening allergies
- MCAS symptoms
- Histamine intolerance
- Autoimmune flare-ups
Musculoskeletal
- Muscle weakness
- Muscle cramps or aches
- Joint pain or stiffness
- Exercise intolerance
- Chronic fatigue
Digestive
- Bloating and gas
- Diarrhea or constipation
- Leaky gut symptoms
- Growing food sensitivities
- Malabsorption
This might be the root cause no one's looked for.
There's now a simple, research-backed screening tool with 90% accuracy to help determine if you're likely suffering from CIRS.
If you've been sick for a long time and nothing has helped, this might finally be the missing link in your healing journey.

